Choral Singing Study Randomized Controlled Trials (CSRCT)
The CSRCT is an intervention based study that seeks to evaluate the efficacy of choral singing in the prevention of dementia. Using Heath Education Program as its control, CSRCT determines the effectiveness of Choral Singing by examining the underlying mechanisms using Magnetic Resonance Imaging (MRI) technique and a panel of peripheral biomarkers in venous blood and urine.
The study aims to get a total of 300 subjects over the span of 4 groups.
Group 1 has been completed as of October 2017.
Group 2 and 3 is currently ongoing.
Group 4 will begin its intervention in September 2019.
The study has recruited 221 of the target 300 subjects and is expected to complete all interventions by December 2020 where data analysis and the writing of publications will begin.
Diet and Cognitive Health in Ageing: A Community-based Prospective Cohort Study (DaHA Follow-up)
The DaHA Follow-up study is the five-year follow up on the previously conducted Diet and Healthy Ageing (DaHA) Study. Subjects who have consented to participate in the follow-up study will be invited to take part in the current study. The results will indicate the relationship between diet and cognitive health among ageing population in the Jurong area.
The purpose of the research study are:
1) To identify dietary factors that are associated with better cognitive health and lowered risk of cognitive decline
2) To investigate the underlying biological mechanisms such as reduced oxidative damage and inflammation
3) To investigate the interaction between diet and genetic factors (such as APOE gene, the most important risk gene for Alzheimer’s disease).
The follow-up study commenced in 2017 and at present the team is still actively recruiting the participants, as well as conducting interviews and assessments. The team has completed the follow-up measurement for 400 participants, out of the targeted 900. The follow up is expected to be completed by the end of December 2019 where data analysis and the writing of publications will begin.